The objective of the research study was to determine the possibility of using potentially probiotic strains of Lactobacillus johnsonii K4 and Lactobacillus casei O12 to manufacture a honey beverage having a appropriate sensory quality and containing viable microorganisms. The research material consisted of honey beverages made of multifloral honey and tap water (12.05 g/100 ml). The beverages were fermented for 2, 3, 4 and 5 days with a bacterial monoculture (after inoculation of approx. 7 log cfu/ml) at a temperature of 30 and 37 ºC. The average count of bacteria ranged from 6.75 to 8.14 log cfu/ml. The growth of bacteria depended on the strain, the time and the temperature of fermentation (p < 0.05). The same factors significantly impacted the mean pH values of all the samples on the subsequent days of fermentation; those pH values ranged between 4.6 and 4.8 (p < 0.05). The fermentation time was a factor to statistically significantly impact the sensory evaluation (p < 0.05). The samples fermented with a Lb. casei O12 strain for 2 days at 37 ºC were given the highest scores in the sensory evaluation. The selected bacteria of the Lactobacillus species can be used to manufacture an innovative beverage having desirable sensory qualities. At this stage of the research, the product cannot be called probiotic; however, the sensory quality and the range of viability of the strains predispose them to continue evaluation of their probiotic properties.